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Cellonis, a Beijing and HK-based biotech company, with its new personalized diabetes treatment
concept has demonstrated an amazing improvement in their treated patients' conditions. The ongoing
clinical study shows the treatment's best case could reconstruct a patient's natural insulin
production and even reverse later complications like kidney failure. Treated patients may have the
chance to return to the normal activities non-diabetes sufferers take for granted.
The clinical study, jointly conducted by scientists and doctors of the Cellonis clinical research
team, aims to help patients be free from insulin and oral drugs, by reconstructing their natural
insulin production damaged by either autoimmune disorder (T1DM) or hyperglycemia and also improve
insulin sensitivity (T2DM). Using injections of autologous stem cells from the patient's bone
marrow, the research team believes that this therapy could help patients return to a life without
annoying everyday injections and drugs.
"Most of the patients in our clinical study are now taking less synthetic insulin or oral
drugs for BG control," says Dr. Chase Dai, Chief Medical Officer at Cellonis. "We appear
to have restored the biological insulin producing function of the body. We are excited to see that
some patients have been treatment-free for five months now, and we believe the effect of the stem
cell therapy can last much longer. We were also encouraged by some other happy surprises during the
clinical study.
"For example, this therapy appears to reverse chronic kidney failure. It was a surprise for
all of my team to observe that the kidney function of a 75- year-old patient improved
remarkably."
This patient had suffered from diabetes for years, gradually developing diabetic foot and
nephropathy. He can now walk freely after having been confined to bed or a wheelchair for six
months, and his quality of life has improved significantly. Moreover, he only needs kidney dialysis
one time a week instead of three times. In a follow-up visit he excitedly told us that he was
hopeful that in the near future he could be completely rid of diabetes.
Diabetes, an increasingly spreading disease, can lead to life-threatening diseases such as
blindness, amputation, strokes, or kidney failure in its natural course. Current treatments,
including insulin, cannot change this situation.
"We believe that our stem cell therapy will bring promising hope for patients suffering from
diabetes and its complications," comments Cindy Hao, CEO of Cellonis. "Personalized
diabetes therapies for patients of various conditions will be developed by Cellonis in the near
future. We believe what we have restored for patients will not only be their natural insulin
production, but also a normal life filled with the activities non-diabetes sufferers can enjoy
daily."
Cellonis Biotechnologies focuses on R&D and the clinical application of novel personalized stem
cell therapies and immunotherapies for patients with diseases including cancer, diabetes and central
nervous system disorders.
June 27, 2010 (PR-USA.net)