Diabetes mellitus of 2nd type treatment
Diabetes mellitus of 2nd type (insulin-independent diabetes) is a chronic disease that develops as a result of the violation of the interaction of insulin (pancreatic hormone) with body cells and tissues.
Risk factors
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overweight or obesity, predominant fat deposition around the waist
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sedentary lifestyle
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diabetes diagnosed in close relatives
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age - the risk of diabetes increases with age, but unfortunately, the number of young people with type 2 diabetes and even children has increased in recent years
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prediabetes and metabolic syndrome
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polycystic ovarian syndrome
According to the International Diabetes Federation the total number of diabetic patients in the world by 2025 will exceed 380 millions. The vast majority will have type 2 diabetes.
High glucose level in blood causes:
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Cardiovascular diseases:
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increased risks of ischemic heart disease, infarctions, strokes, atherosclerosis and hypertension.
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Nervous tissue damage (neuropathy):
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violation of innervation, especially of the lower limbs which causes tingling, burning, pain in the feet and can lead to complete loss of legs sensation
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gastrointestinal problems: nausea, diarrhea, constipations
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erectile dysfunction in men
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Kidney damage (nephropathy):
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violation of glomerular filtration and, as a consequence renal failure
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Vision problems:
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the development of diabetic retinopathy, as well as an increased risk of cataract and glaucoma
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Ischemia of lowers limbs:
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non-healing wounds on the legs which often leads to gangrene and, as a result, amputation of the toes or the limb itself
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bacterial and fungal infections affecting the skin and mucous membranes
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Pregnancy complications:
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increased risk of abortion and pathology of pregnancy
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Treatment of type 2 diabetes mellitus at the Institute of Cell Therapy
The unique method of treatment of type 2 diabetes mellitus using stem cell transplantation has been used for more than 15 years at the Institute of Cell Therapy.
The stem cell treatment method leads to better control of diabetes, namely:
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restores sensitivity of peripheral tissues to insulin (reduction of insulin resistance)
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helps to normalize glucose level in blood
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reduces endogenous glucose synthesis in the liver
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normalizes lipid metabolism
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facilitates to microcirculation improvement in all organs
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protects the walls of blood vessels
These effects contribute to:
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reduction of HbA1c (glycated hemoglobin)
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reduction of the risk of diabetes complications and decrease of severity of their manifestations, if any
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control of glucose content with fewer drugs or only through a diet
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improvement of metabolism and allow patients to feel more active and energetic
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normalization of hormonal and immune status
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improve quality and duration of patients' life
An example of efficient use of hematopoietic stem cells transplantation in treatment of type 2 diabetes based on the clinical practice of the Institute of Cell Therapy
Dynamics of plasma glucose and glycosylated hemoglobin after hematopoietic stem cell transplantation
The Coordination Center for Transplantation of Organs, Tissues and Cells of the Ministry of health of Ukraine together with the Institute of Cell Therapy have performed a clinical study of patients with type 2 diabetes. Within 3 months after transplantation, a decrease in glucose level and glycated hemoglobin level to almost normal values was recorded.
Fat metabolism indicators have been normalized, atherogenic index decreased, biochemical indicators of liver function improved. The positive effect of cell therapy lasts up to 3 years.
Consultation
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